Appetite Suppressants

There are various prescription drugs available to suppress appetite. The first such drug was phenterime and since then many related drugs (Adieux, Fastin, Ionamin) have been developed. All these drugs work on the brain and suppress the feeding center. The major problem with the use of these drugs is their side effects and ability to cause physical dependence. Current FDA guidelines recommend that these drugs not be used for more 3 months at a time. Because of the unpredictable side effects, many physicians even get patients to sign consent forms acknowledging the potential for complications.

Another class of drugs that has shown some effective as appetite suppressants are the SSRI class of anti depressants (Zoloft and Prozac). While clinical trials are lacking, there are a lot of reports on weight loss induced while taking such drugs. Other less popular appetite suppressing agents include diethylpropion, phendimetrazine and mazindol.

Another newer drug used in Europe is Acomplia. This drug inhibits the appetite center in the brain. Also observed is its ability to diminish smoking. Currently there is some concern about its psychiatric effects and the FDA has placed a hold on the availability of Acomplia in the USA.

Two drugs with promising efficacy at promoting weight loss are Xenical and Sibutramine. Both these drugs are known as fat busters. They prevent the absorption of fat from the intestine and can promote a weight loss of 10%-20% over a 4-6 month period.

While drugs do work at promoting weight loss, to ensure that weight loss continues; one must also adhere to a health diet and a drastic change in life style- which means regular exercise.